Exploring programmable self-assembly in non-DNA based molecular computing

1 DNA Computing and Molecular Self - Assembly Area Exam

DNA Computing by Self-Assembly

Information and algorithms appear to be central to biological organization and processes, from the storage and reproduction of genetic information to the control of developmental processes to the sophisticated computations performed by the nervous system. Much as human technology uses electronic microprocessors to control electro-mechanical devices, biological organisms use biochemical circuits...

Computing by molecular self-assembly.

The paper reviews two computing models by DNA self-assembly whose proof of principal have recently been experimentally confirmed. The first model incorporates DNA nano-devices and triple crossover DNA molecules to algorithmically arrange non-DNA species. This is achieved by simulating a finite-state automaton with output where golden nanoparticles are assembled to read-out the result. In the se...

Programmable Assembly at the Molecular Scale: Self-Assembly of DNA Lattices (Invited Paper)

DNA self-assembly is a methodology for the construction of molecular scale structures. In this method, arti cially synthesized single stranded DNA self-assemble into DNA crossover molecules (tiles). These DNA tiles have sticky ends that preferentially match the sticky ends of certain other DNA tiles, facilitating the further assembly into tiling lattices. DNA self-assembly can, using only a sma...

Computing Real Numbers using DNA Self-Assembly

DNA Self-Assembly has emerged as an interdisciplinary field with many intriguing applications such DNA bio-sensor, DNA circuits, DNA storage, drug delivery etc. Tile assembly model of DNA has been studied for various computational primitives such as addition, subtraction, multiplication, and division. Xuncai et. al. gave computational DNA tiles to perform division of a number but the output had...